Sigma-1 receptors and choline

by | 16 Jan 2019 | Study Notes

Photo by Harry Quan on Unsplash

Aaargh, rabbithole! Just learned something, and made a confirmation-bias connection.

Briefly:

  1. Sigma-1 receptors may be amplifiers of neurodegeneration in diseases such as those associated with a CACNA1A allele (and Alzheimers, ALS, etc.). Here’s how.
  2. Choline may help. Here’s how.

I love choline so much right now. More about my personal relationship with choline later.