Tania Melnyczuk

Study notes

My Study Notes record what I am learning. They're mostly about molecular and cell biology. They reflect my knowledge and understanding at the time, and are subject to extensive revision.

Sigma-1 receptors and choline

Sigma-1 receptors and choline

Photo by Harry Quan on Unsplash

Aaargh, rabbithole! Just learned something, and made a confirmation-bias connection.

Briefly:

  1. Sigma-1 receptors may be amplifiers of neurodegeneration in diseases such as those associated with a CACNA1A allele (and Alzheimers, ALS, etc.). Here’s how.
  2. Choline may help. Here’s how.

I love choline so much right now. More about my personal relationship with choline later.